Clinical Data

The following clinical studies support the claims of SYSTANE® Lubricant Eye Drops. To view an available summary of an abstract, click on the hyperlinked study title.

SYSTANE® Lubricant Eye Drops

  1. Christensen MT, Cohen S, Rinehart J, Akers F, Pemberton B, Bloomenstein M, Lesher M, Kaplan D, Meadows D, Meuse P, Hearn C, Stein JM. Clinical evaluation of an HP-Guar gellable lubricant eye drop for the relief of dryness of the eye. Curr Eye Res. 2004. Jan;28(1):55-62. Study summary information
  2. Przydryga J, Hartstein I, Khwarg S. Results of a community-based evaluation of a lubricant eye drop. Presented at: The 107th Annual American Optometric Association Congress; June 23-27, 2004; Orlando, FL. Presented at: the European Association for Vision and Eye Research, Joint European Research Meeting in Ophthalmology and Vision; September 24-27 2004; Vilamoura, Portugal. Pending publication in Current Medical Research and Opinion. View Poster
  3. Meadows DL, Ketelson HA. Physical/Chemical Characteristics of the Human Tear Film that Impacts Performance & Efficacy of Artificial Tear Products. Tear Film and Ocular Surface Society 2004.

SYSTANE® Extends Tear Film Break-up Time

  1. Christensen MT, Stein JM, Stone RP, Meadows DL. Evaluation of the effect on tear film break-up time extension by artificial tears in dry eye patients. Presented at: 23rd Biennial Cornea Research Conference; October 3-4, 2003; Boston, Mass.
  2. Ousler GW, Emory TB, Welch D, Abelson MB. Factors that influence the inter-blink interval (IBI) as measured by the ocular protection index (OPI). Presented at: The Association of Research in Vision and Ophthalmology (ARVO); 2002.
  3. Nally L, Ousler GW, Abelson MB. Ocular discomfort and tear film break-up time in dry eye patients: a correlation. Invest Ophthalmol Vis Sci. 2000;41(4):1436. ARVO Abstract.
  4. Guillon M, Chamberlain P, Marks MG, Stein JM. Effect of Eye Drop Compositional Characteristics on Tear Film. Presented at: The Association of Research in Vision and Ophthalmology (ARVO); April 25-29, 2004; Fort Lauderdale, FL.

SYSTANE® Compatibility with Restasis*

  1. Sall KN, Cohen SM, Christensen, MT, Stein JM. An Evaluation of the Efficacy of a Cyclosporine-Based Dry Eye Therapy when used with Marketed Artificial Tears as Supportive Therapy in Dry Eye. Eye & Contact Lens. 2006;32(1):21-26.
  2. RESTASIS* prescribing information.

SYSTANE® Lubricity

  1. Ketelson HA, Asgharian B, Chowhan M, Meadows D. In-vitro Characterization of Physical Property Attributes for Polymer Systems Used in Artificial Tear Products. Abst. ARVO 2004:No 70.
  2. Korb DR, Greiner JV. Et. Al. Lid-Wiper Epitheliopathy and Dry-Eye Symptoms in Contact Lens Wearers. The CLAO J. 2002: 28(4):211-216.
  3. Korb DR, Herman JP, Greiner JV, Scaffidi RC, Finnemore VM, Exford JM, Blackie CA, Douglass T. Lid Wiper Epitheliopathy and Dry Eye Symptoms. Eye & Contact Lens 2005; 31(1):2-8.

SYSTANE® Pre- and Post-Contact Lens Wear Improves Comfort

  1. Cohen S, Potter, W, Christensen MT. Use of SYSTANE to help reduce symptoms of dry eye associated with contact lens wear. Presented at: the 107th Annual American Optometric Association Congress; June 23-27, 2004; Orlando, FL.

Ocular Protection Index

  1. Ousler GW, Emory TB, Welch D, Abelson MB. Factors that influence the inter-blink interval (IBI) as measured by the ocular protection index (OPI). (Poster presentation) The Association of Research in Vision and Ophthalmology (ARVO), 2002.
  2. Nally L, Ousler GW, Abelson MB. Ocular discomfort and tear film break-up time in dry eye patients: a correlation. IOVS 2000 41;4(ARVO Abstract):1436.

Glycocalyx

  1. Korb DR, Craig J, Doughty M, Guillon J, Smith G, Tomlinson A. The Tear Film: Structure, Function and Clinical Examination. BCLA, 2002.